Agomelatine API

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Agomelatine API Specification

Storage
Keep away from moisture

Molecular Formula
C15H17NO2

Shelf Life
5 Years

Molecular Weight
243.3 g/mol Grams (g)

Medicine Name
Agomelatine

Chemical Name
N-[2-(7-methoxynaphthalen-1-yl)ethyl]acetamide

CAS No
138112-76-2

Type
Other

Grade
Medicine Grade

Usage
Antiglaucoma

Appearance
White or white alike crystal powder

Physical Form
Powder

Agomelatine API Trade Information

FOB Port
ALL INDIA

Payment Terms
Cash Advance (CA), Western Union, Paypal, Telegraphic Transfer (T/T), Cash in Advance (CID)

Delivery Time
2-3 Week

Sample Policy
Sample costs shipping and taxes has to be paid by the buyer

Packaging Details
25kg/drum with double plastic bags inside; packed in a cardboard drum or fiber HDPE drum.

Main Export Market(s)
Middle East, Western Europe, Africa, Eastern Europe, Australia, South America, Asia, Central America, North America

Main Domestic Market
All India

Certifications
WHO,GMP,COA As Per Client Requirement

About Agomelatine API

Agomelatine is an extremely potent agonist at both melatonin receptors (MT1 and MT2), with additional antagonism at 5HT2C. It is a novel antidepressant with many desired in vivo properties, including neuroprotection and neurogenesis in depression-sensitive brain areas.

Agomelatine's efficacy appears to be due to both melatonergic and serotonergic properties. In neurogenesis assays, both in vitro and in vivo, the compound effects were differentially affected by antagonists for MT1/MT2 and 5HT2C, demonstrating actions through all three receptors.

Formula -C15H17NO2
Molar mass -243.301 g/mol
Bioavailability -1%
Protein binding -95%
Metabolism -hepatic (90% CYP1A2 and 10%CYP2C9)
Biological half-life- 1-2 hours Excretion -Renal (80%, mostly as metabolites)

Packaging details:

Packaging details:	25kg/drum with double plastic bags inside; packed in a cardboard drum or fiber HDPE drum.
Storage:	Stored in a clean, cool, dry area; keep away from moisture and strong, direct light/heat
Shelf Life:	5 years if sealed and store away from direct sun light.

High-Quality Medicine Grade Agomelatine

Our Agomelatine API is produced to medicine-grade standards, ensuring safety and efficacy for pharmaceutical manufacturing. Each batch undergoes rigorous quality control, offering confidence in every supply. The powder form, with its white crystalline appearance, is suitable for various drug formulations and meets the expectations of global regulatory requirements.

Reliable Supply Chain in India

Available through a well-established network of distributors, exporters, manufacturers, suppliers, traders, and wholesalers across India, Agomelatine API is readily accessible for both domestic and international buyers. Our streamlined logistics system ensures timely delivery and adherence to quality during transit.

FAQ's of Agomelatine API:

Q: How should Agomelatine API be stored to maintain its quality?

A: Agomelatine API should be kept away from moisture and stored in a dry, airtight container to preserve its stability and prolong its shelf life, which is up to 5 years under recommended conditions.

Q: What is the primary use of Agomelatine API in the pharmaceutical industry?

A: Agomelatine API is primarily used in the treatment of glaucoma as an antiglaucoma agent. It is formulated into medications that help manage this eye condition.

Q: When is Agomelatine API typically incorporated into the pharmaceutical production process?

A: Agomelatine API is introduced during the formulation phase, where it is processed into finished medicine forms such as tablets or capsules under controlled conditions.

Q: Where can I source Agomelatine API in India?

A: You can obtain Agomelatine API through authorized distributors, exporters, manufacturers, suppliers, traders, and wholesalers throughout India, ensuring access to authenticated and quality-assured material.

Q: What benefits does using high-quality Agomelatine API offer to medicine manufacturers?

A: Utilizing high-grade Agomelatine API enables manufacturers to create effective, consistent, and safe medicines that meet regulatory and market expectations, strengthening their product reliability.

Q: What is the appearance and chemical identity of Agomelatine API?

A: Agomelatine API presents as a white or nearly white crystalline powder. Its chemical name is N-[2-(7-methoxynaphthalen-1-yl)ethyl]acetamide, with a molecular formula of C15H17NO2 and a molecular weight of 243.3 g/mol.

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