Doxylamine Succinate

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Product Description

Doxylamine is a first-generation antihistamine. It can be used by itself as a short-term sedative and in combination with other drugs to provide night-time allergy and cold relief. Doxylamine is also used in combination with the analgesics paracetamol (acetaminophen) an analgesic/calmative preparation, and is prescribed in combination with vitamin B6 (pyridoxine) to prevent morning sickness in pregnant women.

Specification:

Test Items	Specifications	Results
Appearance	White or almost white crystalline powder	Conform
Solubility	Very soluble in water, freelysoluble in alcohol	Conform
Identification	1) Melting range:103-108 2) Ultraviolet absorption: UVmax=262.0nm 3) Organic Nitrogenous Bases 4) Succinic acid melting range:184-188	105 262.0 nm Conform 186-188
Loss on drying	<0.5%	0.3%
Residue on ignition	<0.1%	0.1%
Related substances(GC)	Total impurities<2.0% Single impurity<1.0%	1.9% 1.0%
Residual solvents	Diethyl ether<0.5% Acetone<0.5% Iso-propyl ether<0.5%	0.4% 0.4% 0.4%
Assay	98.0%-101.0% (Calculated on anhydrous substance)	99.2%

Packaging details:

Packaging details:	25kg/drum with double plastic bags inside; packed in a cardboard drum or fiber HDPE drum.
Storage:	Stored in a clean, cool, dry area; keep away from moisture and strong, direct light/heat
Shelf Life:	5 years if sealed and store away from direct sun light.

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